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Andrew Hon FBCI, EIoSCM Hiles Rothstein Publishing PDF




By Andrew Hiles



A Cache SLA should include the generic elements of a SLA as outlined in Chapter

One above. In addition it could cover the following:



The objective of the cache service is to provide efficient access to www servers through optimising limited bandwidth. This is achieved by storing cachable responses to reduce the response time and network bandwidth consumption on future, similar requests.



Apart from definitions to identify the operator, customer / user and the service itself, definitions should be provided to avoid ambiguity of technical terminology, e.g.:







Cache: A program's local store of response messages and the subsystem that controls its message storage, retrieval and deletion.

Client: Any Customer's client equipment configured to use a proxy cache in accordance with the HTTP protocol

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Andrew Hon FBCI, EIoSCM Hiles Rothstein Publishing PDF

E-Business Service Level Agreements:

Strategies for Service Providers, E-Commerce and Outsourcing




This chapter outlines the history of outsourcing and *SP services. Issues of service "ownership" are raised and the thorny topic of outsourcing disputes is covered. *SP supply chain dependency – and solutions – are identified. We cover supplier evaluation and selection;

Invitations to Tender and associated SLAs and contract matters. Case studies are provided.


By Andrew Hiles



According to industry experts IDC, the worldwide market for IT services will surpass half a trillion dollars by 2004. The biggest winners in this spending are likely to be e-Sales, Enterprise Resource Planning, Customer Relationship

Management and supply chain management applications. Routine administrative functions like Financial Accounting and payroll can also be outsourced, removing some of the drudgery and avoiding the overhead of software maintenance and the hassle and danger of frequent application changes to comply with new financial legislation and regulation.

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CHAPTER 17 - The Hypotonic Infant, Thornton B.A. Mason II, Darryl C. De Vivo

David S. Younger Rothstein Publishing PDF


The Hypotonic Infant

Thornton B.A. Mason II, Darryl C. De Vivo


Infantile hypotonia is suggested by the constellation of physical signs observed when a hypotonic or floppy infant is placed into a series of suspended postures. When placed supine with the arms lying flail to the side and the hips externally rotated in the frog-leg position gentle arm traction and elevation of the infant from the supine position causes the head to lag in retroflex at the neck (Figure 1). When supported in a seated position the hypotonic infant veers forward because of poor axial tone (Figure 2). With vertical suspension and the child held upright under the arms, the hypotonic infant will begin to slip through the examiner’s hands. In prone position with the trunk supported, the affected infant slumps over the examiner’s hand in an inverted U posture with the head and limbs limply hanging like a rag doll (Figure 3). When individual joints are passively moved by the examiner, there is decreased perceived resistance. The head of a hypotonic infant should be kept in midline during this evaluation of limb tone because turning it may inadvertently evoke a tonic neck reflex response promoting lateral tone asymmetry.

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Chapter 12: Putting Plans and Teams in Action

Bruce T. Blythe Rothstein Publishing ePub
12 Putting Plans and Teams in Action

As with any project, you will want to prioritize its elements, and establish a schedule for its implementation. You will want to clearly document the schedule you set. If a crisis occurs before your plan is fully in place and tested, or not yet complete at some locations, this documentation can serve as defensible proof of your intentions. If your company is later accused of negligence, such actions can help you pass the “reasonable person test” that we discussed earlier in this book. This chapter will help you to: Create and train effective crisis teams with the right mix of participants. Exercise and practice the plan using realistic scenarios. Integrate crisis response throughout the organization. Debrief participants in exercises and real crises to improve the plan. See All Chapters
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CHAPTER 11 - Neurologic Hereditary Metabolic Diseasesof Infancy and Childhood, David S. Younger

David S. Younger Rothstein Publishing PDF


Neurologic Hereditary Metabolic Diseases of Infancy and Childhood

David S. Younger

Neurologic hereditary metabolic disease (NHMD) can lead to motor disturbances that become clinically evident from the neonatal period through early and late infancy to childhood, each with a purported biochemical, molecular or cytogenetic defect, and unique genetic inheritance pattern. An appreciation of these disorders is essential to a clear understanding of the natural history, prognosis, and therapeutic decisions, including genetic counseling for prenatal diagnosis and carrier detection, and in the selection of potentially effective treatments to preserve neurological function and forestall deterioration. Even though each of the NHMD is exceedingly rare, the group as a whole is not, with an estimated prevalence of 1:5,000 (1).


The vast number of NHMD can be categorized into one of three possible etiopathogenic disturbances causing: 1) Storage of large molecule metabolism such as glycolipids and glycoproteins as occurs in lysosomal, leukodystrophy, and peroxisomal storage disorders affecting multiple visceral organs and the nervous system over time; 2) Altered small molecule metabolism as, for example, amino acids as in amino acid and organic acidurias, and urea cycle disorders that lead to early acute toxicity; 3) Glycolytic, fatty acid, and mitochondrial metabolic disturbances with deficient energy production resulting in slowly progressive and static motor disturbances and intermittent crises. Another method of classification is by age at onset from neonatal to early and late infancy or childhood. The genetic basis of the NHMD includes autosomal recessive (AR), dominant (AD), X-linked

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