657 Chapters
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Relationship Among Cat–Owner Bond, Cat Behaviour Problems and Cat Environment Conditions: A Study with 1553 Spanish Cat Owners

Denenberg, S. CABI PDF

�Relationship Among Cat–Owner

Bond, Cat Behaviour Problems and Cat Environment Conditions:

A Study with 1553 Spanish Cat


Natalia Bulgakova1*, Sandra Burgos1, Paula Calvo1,

Jonathan Bowen1,2 and Jaume Fatjó1

Chair Affinity Foundation Animals and Health, Universitat Autònoma de

Barcelona, Spain; 2Royal Veterinary College, University of London, UK


Conflict of interest: The authors declare no conflict of interest.

Keywords: cat–owner bond, cat behaviour problems, cat welfare


Owners’ bonds with their cats may affect awareness of cats’ well-being and adherence to behavioural treatment. Our aim was to explore relationships between the cat–owner bond, cat welfare conditions and cat behaviour problems.

Materials and Methods

We conducted an online survey, which included the Cat Owner Relationship

Scale1 (CORS), a cat welfare scale, and a cat behaviour problem assessment. Cat owners were recruited through social media networks. We analysed correlations between scores for CORS, welfare and behaviour problems. We also analysed all

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The Effects of a Nutritional Supplement (Solliquin) in Reducing Fear and Anxiety in a Laboratory Model of Thunder-induced Fear and Anxiety

Denenberg, S. CABI PDF

The Effects of a Nutritional

Supplement (Solliquin) in

Reducing Fear and Anxiety in a

Laboratory Model of Thunderinduced Fear and Anxiety

Gary Landsberg1*, Scott Huggins2, Julie Fish3 and

Norton W. Milgram1

CanCog Technologies, Toronto, Ontario, Canada; 2Nutramax Laboratories

Veterinary Science Inc, Lancaster, South Carolina, USA; 3Vivocore Inc.,

Fergus, Ontario, Canada


Funding: This project was funded as contract research by Nutramax Laboratories to

CanCog Technologies.

Conflict of interest: Scott Huggins is an employee of Nutramax Laboratories.

Keywords: dog, l-theanine, Magnolia officinalis, Phellodendron amurense, noise-induced anxiety


The objective of this study was to evaluate the effectiveness of a nutritional supplement in reducing the anxiety response of Beagle dogs in a thunderstorm test model of noise-induced anxiety after one day of test article administration and after a double dose of the product following 7 days of administration. The supplement (Solliquin) is a nutraceutical intended for relief of clinical signs associated with fear, anxiety and stress, which contains a proprietary blend of l-theanine, extracts of Magnolia officinalis and Phellodendron amurense, as well as a whey protein concentrate previously found to have anti-anxiety effects. (Araujo et al., 2010;

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Medium 9781786390394

5 Discovery of Novel Antimicrobial Peptides Using Combinatorial Chemistry and High-throughput Screening



Discovery of Novel Antimicrobial

Peptides Using Combinatorial Chemistry and High-throughput Screening

Charles G. Starr and William C. Wimley*

Department of Biochemistry SL43, Tulane University Health Sciences Center,

New Orleans LA, 70112-2699, USA


The field of antimicrobial peptide (AMP) research has now spanned 4 decades in which many hundreds of AMPs have been discovered, designed or engineered. Yet, despite a vast literature, obvious sequence– structure–function relationships are rare, creating a bottleneck in the discovery of novel AMPs. Instead of rigorous structure– function principles, AMP activity may be best addressed using the physical chemistry concept of ‘interfacial activity’, which does not currently allow for explicit prediction and engineering of AMP activity. In this chapter we address a way to circumvent this engineering bottleneck: combinatorial chemistry and high-throughput screening.

Combinatorial methods are first discussed from the perspective of library synthesis techniques for both indexed and nonindexed methods. This is followed by a discussion of available high-throughput

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2: Comparative Mycobacteriology of the Mycobacterium tuberculosis Complex

Edited by H Mukundan, Los Alamos National Laboratory CAB International PDF


Comparative Mycobacteriology of the

Mycobacterium tuberculosis Complex


Stephen V. Gordon1* and Marcel A. Behr2

University College Dublin, Dublin, Ireland; 2McGill University Montreal and McGill International TB Centre Montreal, QC, Canada


I feel quite confident that the comparative study of tubercle bacilli will lead to some definite understanding on certain important questions, and eventually to more light on the whole subject of tuberculosis from the preventive as well as the therapeutic side.

(Theobald Smith, 1898)

The Mycobacterium tuberculosis complex (MTBC) is a group of highly genetically related pathogens that cause tuberculosis (TB) in mammalian species. However, the very name of the complex underlines the fact that our knowledge of these pathogens is dominated by studies on the human pathogen, M. tuberculosis. Of course this is entirely justified; M. tuberculosis is a major global pathogen that exacts a horrendous burden in terms of mortality and morbidity so it is appropriate that it is the cornerstone of the complex. In the same way as M. tuberculosis is the best studied human

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1 Introduction

Elof Axel Carlson Indiana University Press ePub

With rare exceptions, animals consist of sexually reproducing populations that are roughly half male and half female—at least that is a human perspective that is applied to other mammals, and generalized to all other animals. An observant individual will notice roaches mating rear end to rear end or horseshoe crabs on the beach in springtime mating with the male mounted on a female, reinforcing the idea that the image of human intercourse can be generalized. I can observe fruit flies mating in the same way without use of a microscope, and I can even tell which is male and which is female if I am looking at a solitary fruit fly resting on my finger.

But that idea of universality is undermined if I observe copulating earthworms, which seem to be engaged in some sort of symmetrical mutual engagement. The ambiguity of the earthworm’s hermaphroditism is also present in most flowering plants. Students learn that pollen bearing stamens are present in the same flower with female components—assigned scholarly names like stigma, style, and ovary—but that is also not universal.

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