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238 A Practical Manual of Pharmaceutical Engineering

REFERENCES

1. R.H Perry, D. Green, Perry�s chemical engineer�s handbook, 6th edition, Mcgraw-Hill book Company, Singapore, 1984.

2. W.L. Mc- Cabe , J.T.Smith, P.Harriott, Unit operations of chemical enginnering, 5th edition, McGrawHill Book company, Singapore, 1993.

3. M.E Aulton, Pharmaceutics, ELBS Edition, Churchill Livingstone Ltd, Hongkong, 1990.

4. W.L. Badger, J.T Banchero, Introduction to chemical engineering, Mc Graw-Hill Book Company,

Singapore,1955.

5. E.A. Raswlis, Bentley�s Textbook of pharmaceutics, 8th edition, Bailiere Tindal, London, 1977.

6. S.J carter, Cooper and Gunn�s Tutorial pharmacy, 6th edition, Kothari Book Depot, Bombay, 1972.

7. L.Lachman, H.A. Liberman, J.L Kanig, The theory and practice of industrial pharmacy, 3rd edition,Lea&

Febiger, Philadelphia,1985.

8. Martin, J.Swarbrick, A.Cammarata, Physical Pharmacy, 3rd edition, Varghese publishing house,

Bombay, 1991.

9. C.V.S Subramanyam,J.Thimmasetty,Sarasija suresh, V KusumDevi, Textbook of pharmaceutical engineering, Vallabh Prakashan, Delhi, 2000.

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A PRACTICAL MANUAL OF PHARMACEUTICAL ENGINEERING

Copyright © by Laxmi Publications (P) Ltd.

All rights reserved including those of translation into other languages. In accordance with the Copyright (Amendment) Act, 2012, no part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise. Any such act or scanning, uploading, and or electronic sharing of any part of this book without the permission of the publisher constitutes unlawful piracy and theft of the copyright holder’s intellectual property.

If you would like to use material from the book (other than for review purposes), prior written permission must be obtained from the publishers.

Printed and bound in India

Typeset at Shubham Composer

First Edition: 2015

UPE-9744-195-A PRAC MAN PHARMA ENGG-SON

ISBN 978-93-83828-43-2

Price: ` 195.00

Limits of Liability/Disclaimer of Warranty: The publisher and the author make no representation or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties. The advice, strategies, and activities contained herein may not be suitable for every situation. In performing activities adult supervision must be sought. Likewise, common sense and care are essential to the conduct of any and all activities, whether described in this book or otherwise. Neither the publisher nor the author shall be liable or assumes any responsibility for any injuries or damages arising herefrom. The fact that an organization or Website if referred to in this work as a citation and/or a potential source of further information does not mean that the author or the publisher endorses the information the organization or Website may provide or recommendations it may make. Further, readers must be aware that the Internet Websites listed in this work may have changed or disappeared between when this work was written and when it is read.

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74 A Practical Manual of Pharmaceutical Engineering

Where, d rs ro g

= Diameter of the particle (m)

= Density of the particle(g/cc)

= Density of liquid (g/cc)

= Acceleration due to gravity (m/s2)

From this equation it is possible to determine the terminal velocity of particles of known diameter.

Say suppose particle of size 40 mm, 20 mm etc.

If a suspension taken in a container of known volume, let the height of the suspension in the container is Ho. It is possible to determine the velocity of settling,

V = Ho/t

� (Eq: 18.2)

After rearranging the equation one can find out the settling time for particles of interest. By applying this concept it is easy to separate particles of different size by pre calculating the time for them to settle completely. This experiment allows an easy mode of separation of particle of interest by performing simple decantation procedure.

PROCEDURE

1. Prepare slurry of calcium carbonate in water (5 g/100 ml).

2. Add this slurry into a beaker (I) and make up to the mark depending upon the capacity of the beaker.

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182 A Practical Manual of Pharmaceutical Engineering

EXPERIMENT

47

EVALUATION OF MATERIALS USED

IN PHARMACEUTICAL PACKAGING—

CORRUGATED BOARD

AIM

To evaluate the given packaging material (Corrugated board).

REQUIREMENTS

Corrugated board

(Cut in to pieces of 5 inch ¥ 4 inch)

(2 pieces)

Screw gauge

(1)

Scale

(1)

Beaker

(1)

Tray

(1)

Fractional weight box

(1)

PRINCIPLE

Corrugated board can be defined as the structure formed by gluing one or more fluted corrugated medium to one or more flat facings of liner board. It has been used as a packaging material for more than 100 years and still maintains a healthy share in the market despite increasing competition from plastics. The major advantages of the corrugated boards are:

1. High stiffness to weight ratio

2. Reasonable shock resistance and cushioning properties

3. Fully biodegradable and recyclable

4. It is versatile and can be used for various packaging requirements of different industries

Corrugated board usually consists of two basic components. Line board and corrugating medium.

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