15 Slices
Medium 9781591201366

11. Selenium

Hoffer MD PhD, Abram Basic Health Publications ePub

CHAPTER 11

SELENIUM

It is difficult to establish strong correlations between any diseases and any one nutrient when a large number of nutrient factors are involved. H.D. Foster (1992) in his excellent review concluded that the evidence for a negative correlation between selenium intake and the incidence of cancer was strong. In one twenty-seven-country survey, breast cancer mortality correlated strongly and negatively with dietary selenium. However, case control studies yield conflicting data. Some workers find no difference in blood selenium levels between breast cancer cases and controls, while others find they are low in the cancer cases. Prospective studies also yield mixed data. One study on 4,480 subjects, of whom 111 developed cancer, showed a significant but small decrease in selenium in the patients who developed cancer.

More recent reviews confirmed Foster’s conclusion. A study by Cornell University and University of Arizona showed that patients taking selenium had a 41 percent less chance of getting cancer compared with those taking a placebo. The treated group experienced 18 percent less mortality. Wahrendorf, Munoz, and Lu (1988) supplemented the diet of people living in a high-risk area in China for esophageal cancer. They found that at the end of the trial, individuals who showed large increases in retinol, riboflavin, and zinc blood levels were more likely to have normal esophagus tissues when they were microscopically studied. Yu, Mao, Xiao, et al. (1990) gave 300 micrograms of selenium to forty healthy miners in a double-blind experiment to test its safety. They concluded that this use of selenium was safe and effective in humans with low selenium status, and that selenium protected lymphocytes against DNA damage. Cancer Research announced on June 15, 2003, that some genes were related to incidence of breast cancer and that these genes were less responsive to selenium stimulation. Over a hundred animal and dozens of epidemiological studies linked high selenium state with decreased risk of cancer. On February 21, 2003, the Food and Drug Administration announced the validity of two health claims: (1) selenium may reduce the risk of certain cancers, and (2) selenium may produce anti-carcinogenic effects in the body.

See All Chapters
Medium 9781591201366

13. The Therapeutic Program

Hoffer MD PhD, Abram Basic Health Publications ePub

CHAPTER 13

THE THERAPEUTIC PROGRAM

We can no longer ignore the extensive data that is already available in the medical literature regarding the orthomolecular therapy and the value of vitamins in cancer treatment. This data contains conclusions of independent physicians with no ties to the drug industry. They have not sought fame and fortune by their studies, and their only goal was to improve the results of treatment for their patients. They did not have the support of the medical research establishment, or the large grants needed by institutions before they perform clinical studies. They didn’t do prospective randomized controlled experiments because they didn’t have the resources, financial or otherwise. But their clinical data is every bit as strong, perhaps much stronger, than the data accepted by the medical community from the early noncontrolled studies on the modern tranquilizers when they first came into use between 1950 and 1960. By the end of 1960, we knew that these powerful drugs were active. The controlled experiments that followed simply confirmed what was already general knowledge. Why were these uncontrolled studies accepted while the studies on vitamins are ignored? The difference is that the drug companies poured millions into promoting their patented tranquilizer compounds, and no one is doing the same for orthomolecular treatment of cancer, because vitamins can’t be patented.

See All Chapters
Medium 9781591201366

5. Vitamin B3

Hoffer MD PhD, Abram Basic Health Publications ePub

CHAPTER 5

VITAMIN B3

Vitamin B3 is the anti-pellagra vitamin. Adding niacinamide to flour almost eradicated pellagra, a disease that was a major scourge in the Southeast United States until the cause of pellagra was discovered. There are several forms of vitamin B3. All are equivalent as vitamins, but there are differences as well. Niacinamide (also known as nicotinamide) is the one most commonly added to multivitamin preparations because it does not cause vasodilatation or flushing. It has no effect on blood lipid levels, and has not been tested for any protective effect against vascular disease. Niacin (also known as nicotinic acid) acts as a vasodilator when it is first taken. It is the gold standard for lowering cholesterol, triglycerides, and lipoprotein A, and for elevating high-density lipoprotein cholesterol. It also decreases deaths in patients who have already had one coronary. It is available in no-flush forms, which have to be carefully formulated. Inositol niacinate is a combination of two vitamins, inositol and niacin. The niacin is released from this compound so slowly that it does not cause flushing. It also has an effect on lipids, but it is not as effective as niacin. All the forms are equally therapeutic for the arthritides (inflammations of the joints), for healing, and for cancer. When I think circulation should be improved, I prefer niacin as a vasodilator. For my cancer-treatment program, I use 300 mg to 3 grams daily.

See All Chapters
Medium 9781591201366

3. Nutrition, Diet, and Vitamins in the Orthomolecular Program

Hoffer MD PhD, Abram Basic Health Publications ePub

CHAPTER 3

NUTRITION, DIET, AND VITAMINS IN THE ORTHOMOLECULAR PROGRAM

Orthomolecular medicine is often labeled as an alternative or complementary medical practice by traditional practitioners. Such labeling attempts to ignore the fact that orthomolecular medicine was established by respected, experienced research scientists, and is recognized and practiced by many medical doctors who have seen the value of its theories. Orthomolecular medicine does not undermine current medical practices; it provides additional preventive and treatment options to patients based on sound nutritional and biological principles. The basis of these principles is founded on nutrition, diet, and the positive intake of supplements that can assist the body in fighting disease. This chapter describes the importance of these nutritional elements, and how vitamins and minerals can help combat diseases such as cancer.

The Importance of Nutrition and Diet

All organisms live in a very intimate relationship with their environment. The external environment provides the food supply and nutrients essential for life, directly influencing the organism’s internal environment and health. This is a complex interrelationship that is subject to continual fluctuations. Over evolutionary time, all species have had to adapt their internal systems to survive these external changes and maintain health. Of all the external influences, there is nothing more important than good nutrition.

See All Chapters
Medium 9781591201366

15. Cancer and Schizophrenia

Hoffer MD PhD, Abram Basic Health Publications ePub

CHAPTER 15

CANCER AND SCHIZOPHRENIA

I have been working with the hypothesis that adrenochrome is involved as one of the main factors in the cause of schizophrenia since 1952. Adrenochrome is an oxidation product of adrenaline (epinephrine). All of the catecholamines can be oxidized in the same way, dopamine into dopachrome, for example. I described this hypothesis and the hallucinogenic properties of adrenochrome in The Hallucinogens, which I wrote with Dr. Humphry Osmond.

Catecholamines

Brain chemicals that act as communication carriers between nerves. These include dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline).

Adrenochrome is also toxic to mitosis, the process of cell division, so it appeared plausible that there would be a natural antagonism between cancer and schizophrenia if our hypothesis was correct. Since cancer is the result of uncontrolled cell division, it could not coexist with adrenochrome. If a patient made too much adrenochrome due to extreme amounts of adrenaline oxidation, he could develop schizophrenia but not cancer, because the adrenochrome would inhibit cell division. If a patient did not make enough adrenochrome, he could get cancer but not schizophrenia, because there would not be enough adrenochrome present to exert its hallucinogenic properties.

See All Chapters

See All Slices